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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4aadfe1a99b133408b0df4ea9340aadebfe291a712ae43fc48fcf3a4a4a08ad5' 
  AND token = 'NQCY+ENG1ni/zRJ5NlkyD8Z5z84VUKa7+BjvKeUBtYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}