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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '850a99a64d35b1dff3a82ddf0d7708e7891074711371453649d0150a476b55a2' 
  AND token = 'kkvz+B8j8oPKsX4Vo5jXntKJoGIMAaE78BuXtJE90ZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}