SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '420ee724aa24e67aed64f9af17046e4ecce7cada7cfde7dd315d9c76040d6e34' 
  AND token = 'SCx3RrshmJu84FOYwQTRUNca1xHp0kJ8reYOJpiQrtY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}