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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '122bd000d07efef965aa90d2dbe0e529f3bf565504eb6932711d5e18fca84721' 
  AND token = 'TM/73NRBoSKu/bI2LL+MS5mbhoLgXk4Pb8m2VfYkMCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}