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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8fd263b2cb17cf3418a620f2ea63b2d560242dd6fd5df942b553e1f75df8ee6' 
  AND token = 'iC1wP34v0gqK/DUoc8bDTCcKSGspWRua/yIOTRdqsDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}