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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7c8cd96924ee5c32c166a1487b93e05fb8576c5be5e1dad0a1699556daa8a00' 
  AND token = 'vk40cYUAuA4hyuUrCCmTm6QqHMN7lOm3DZeE+SYVWw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}