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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a2177b84bc7d9a77b631a8fbe8d2951f33c1627751a44e6d40dcd08be6a1a4a' 
  AND token = 'AZkaK+rZKEeDy/HdvIg3KvcLnyuYIJyMbs3VX7QIEGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}