SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbe9b766f6338c73681c0f60b31d0e83c04317882a902757cd6770017315c495' 
  AND token = 'sjWT+pRQKCpU6KjlBR1rklzDOPDM5imMeRUF6KziKqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}