SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f08f3ec3b745298c0439bd23ce47cdeaaca78e247406e950a401bd48a9df2182' 
  AND token = 'G/ga9TefI/1GCyuYWT4UUcOiqp/96HFGQ9wkgpJC/nE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}