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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ae1b8f88aaade05c8e79c70b0b80af5100a06d517e7c2e082fe2e2b05eb1e3b' 
  AND token = 'gP3oN8nJJ+sHWQSxzxJryQxOdEqEmAsOvftmBB7OPX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}