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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec8684898205b46efd2ad6343cb2ea87c5ad6ac609225f8e396bff538777c0f5' 
  AND token = 'aS+7nsOcfmE90eFk4gsE9bBhchz3YzlMtrGqY7Xe/Ok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}