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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70ecd0c77f05a0481d61b807a9c7ec515c35e4ba3f4a9603962d1195385ca939' 
  AND token = '++0FzxeWbdElCCXb9L5Xm5YLOmY5yw94RpvBIJvLVtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}