SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53152e956acb8f4b4bcf1b07c2a7aa3c5b3610bd34458685a90583bf6120975b' 
  AND token = 'luoZB+82Jcs3zTarVC9pEC0Vta1wtpCfgSpg3VkDcyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}