SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c328249d4b7bf4313b96752926cbc09a0b0940262294939a3edd0dea31f6bf5' 
  AND token = 'EheRX3tLbODbRhZ4xCLUVzlKadAOA5BA2Kj/smI0eDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}