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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4a450edbb3309d833db366dec2f584fc95769eea5edc8e12d5f7b86ca826141' 
  AND token = 'XyF4M082aUPTpQWuLVrnmt6qKOzm2RMXDDZ+RlxjdZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}