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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d92e41b2bc446ee26034bd60eb3a74b28c2db5a813627601ade9e3fd4ad496d' 
  AND token = 'ZYSDetrAIpyx66z0VHdC1q5qsxWbKE4Jx7YBrt+OdWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}