SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7af37e84e4f415b5d5d4639d063f047162ef9a3173c354a0eb204c2286c63ddc' 
  AND token = 'F0SYChVgLABZAy1CCR6i8L05hwTvbV3EAVIEIUS6Ecc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}