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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e9e5ef92abc218da2c3e9addff07d946cdeca53e6c7b374ee4a5020954d2ff' 
  AND token = 'Fq4+aLlDTgASJ4RQr2dpxSLB/lTnmWOrSLobBL7rN+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}