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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4aff4a12df19e9cb020fb52614c1c00ad3fc16a2dedf8068980488e725c6bb6' 
  AND token = '71GF7P2V3QMmd+VfsypqnmUTpPmCSYTVU74HtTIcgeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}