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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b22ffb70f4616dbb74830a1c69ffc79166c3611b8a5c02e65c1de4e516c3a1e' 
  AND token = 'OFLYPI1x6hsy6rPgnqhMylWocNKqNP4EIgvQQNG4T4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}