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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99e47f59812df6406e63e2dc52a54d68db3e5522433fbeebf74a7f2a3dfc8d29' 
  AND token = 'hig/s/SI3g9hPUa/AuuxkrdvxfKq7xPj8oZUEffcZ40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}