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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5423278b6747967a4ff7c9b9f4a43ac17d9cc212ced8da349573d9110a7f24c6' 
  AND token = 'Vr01ytGU5KLJ8vexIdzR7yH6HTELC1LN0M1wdCBKyzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}