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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4188d62a931300e9f98fd2d0dad5e26bfefa8e309497cec2b9a9a9d39049079f' 
  AND token = 'lCY0pS0132YPQgd/qqt5eY35IVbxQLq2NMecKlTMQ2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}