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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cbf4db5b8903659afb4d79c4d19121c3efee195fb2019ae611d49ed2fc5f4b5' 
  AND token = 'y9JXxsaQE8B4C4D36NdnZAZkL96XnCXLxrjRmTr29E0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}