SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91e8ac356b965492ec9a365db983d8b6a36a50ffb1f4aa82998240d00e13a46a' 
  AND token = 'Wi1YVsxkEn4HWYJ58uGV1KQFMQ+lIUXGMx4CASdivuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}