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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '619b6a2807ed933781da9644f3a1bf3fbb66828ad618799b5fad9677fb01300f' 
  AND token = '6d+TT6wBGgiLRYwL8iUXoYvwox3jQ9Vbb0pyjCTIFps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}