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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06a5e0a0b52c1a2f47d8c3ee65f2f329a07302717342272203e3b6174b34b190' 
  AND token = 'lkPtOKQLJ128DzCYdAs/5MzzkuqlmhZwl9B0D/Z3hzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}