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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79ba42a6e372ce3f40e9834620094c00c437bdd0831180f9b0dddc02b0b35ade' 
  AND token = 'yi3NAis83Wq8IsH/yj83cK0M0BazRvlTiB4Z9yBYQ3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}