SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f67addce2bc66efcda91f03c5b45cf0b1a7450702e94635b4245ad4bdbf70b83' 
  AND token = 's1TFizJLJpboF5o6IQTfYKeTWQEPpt34lrkMi6uARwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}