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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20fad9304421bd73fd4afbb7df676bf8b553ea9e43a7dd10b8cdf7286c29d3f5' 
  AND token = '/o00jVb2wC+B/dokhbGVkADzhZkG0Pfu3ky6waSAySw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}