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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3108b52937ca80baa409b9307b40f0b078602c0139b265b4f3e59e41ef4356bd' 
  AND token = 'CZ8b4pr+cqNsRUCpMRuSjSGLFCRFsATbNpjUkbD4Mik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}