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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b0f42738f7f1105a328f2ef67b3343908009375d9f54233c703f73dd4a95c68' 
  AND token = 'eCmc6TNFLznqGlwMAKHT7BZx0pZO905e691YAzFnErI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}