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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b54ead1bf7d3b635b3ee0952f787305f9e8a66131b5df10863999a0e23eeff18' 
  AND token = 'DKatEVAqsLXMXbS6UCi+A3zNCdjoVZe/FARDbAoTlUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}