SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37e0585f21f8e4654ee23ffb682d63502bea4bfdc57f4a3d2d0b0d523a7ba54d' 
  AND token = 'oyY8Si+/7+dy3hILHVAEp9Xwi26AWlEYsapmkmtXGf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}