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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9932bf4d5e094d552f3a718f87680b5a58f4937a46afc5eafa693c284143935' 
  AND token = 'jEcSUnhQyPLwKOlRxQDHahrG+jlh4ocUP4QDRQ+lrdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}