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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4579d8f1e44e1be63faa6e1a71ed08c1849f0745a60ddb2681384ce7ca0d1e57' 
  AND token = 'STIldJQdyIz9Pnyeq/60JQV2Rhw4Qv6Qb0oxOMBflM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}