SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df6098f1ee71bb024f52d2e87dee4dd923855b29fce8ddb0561b306de368f6c1' 
  AND token = 'ODMYbH1YH8UWyh2YIow+7bjo4cYDxn16eZxyfC4cx5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}