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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46ad62d8e677c73962157a04faf88f40ecabddfcaeebad8017d2845ee81d51fe' 
  AND token = 'jVGs4pHFu2yn68pqYe3l4KZMHTMXkMMubG0Vv4F/KDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}