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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f1abce365bd79a3c85d03fc16b8295bb26c3c4210044ce8396a1cc3a2278357' 
  AND token = '34eSzQu3ZQ4Y4r77lOdhINwpYxUpdxCmQVzb27Z2KV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}