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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a53b7a09bdc84f0a58e0c2e91bef79dfb90bddcd2f4f96de9821db2bd5ee0b37' 
  AND token = '78zBwfuTy70FyVoxETf2Yq9J1Y5NdtK9J8bhMd8HQaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}