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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a6d951d2af33fc3654e110af6382d696971a286117965db983e55cc42c4a72e' 
  AND token = 'etCO50Jc89ULnF8YkSSUz5YpcO8oMdpU88ip2ssEeZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}