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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39440f69be80d9ac20c81b83e70ba80882979d189efbb073ddab76883cd2cca5' 
  AND token = 'mYCTshVGfXU+y3/cEaSZqbn2x2MtIj4r15Ee2qA3NtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}