SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d3540d967ae6e49eb48e85d693f87040056c5cfdba71ff4c7373f2ebd7d213d' 
  AND token = 'uVXYAxTJ8k6P5OA0s4bqOlXia3dFf7d6EmZmw+dRS0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}