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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9329a4049223152209106d98ccae223345944fa96634c866f8f974f634ab2e1f' 
  AND token = 'QETmZuZpAoQK7B2chbXgbUPT15ULtIloObea63o36KQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}