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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49ed75f29a64c73f83a7dcefcf2c5f00eb045d559e51d0b3e10902da78e926e6' 
  AND token = 'YaqRaLoTNo1ucDi18rhlA7kNbjb+WCDARjMHNWnNL6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}