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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b7a5a915e5f16afdaef48f528676ba15d3cf8b68dd9c2685ae78ff1a944c299' 
  AND token = 'MSVLUL+dsmK/bmzd21sw5pmo/bDanFlDXK10zA1tclU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}