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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad221e33b5bad0b916ed11466fe247628a07acb86aff18f72bde7e71938ad54b' 
  AND token = '0CsoTxj30NkmirPZGpMdaLqojuQDTiIm0aZzfF1p9Aw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}