SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3308f17a942834e52be22ca6993e57b6e6dbf7128cb523cc7541b32a28d91536' 
  AND token = 'EEilznzFWDK2cAopxwU9Nt46CZhmDtEAk5YjAJ0m5OE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}