SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1ceae56cd3236d61e89e56dcb6148023782e8895a6c75c2637ea3006e070fe4' 
  AND token = 'x528xH+irSPVn0Aq0fDqBNkh1u0Zx2jwqtko0XtmNrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}