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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4cc7b15b6d70f12305109950715b2d0303a584bee543c55f27c42bc01868509' 
  AND token = '4um8gY9SpmM1RAhM1Gi8crCRAjPegdLcUFaJSjlXLVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}